- June 2013, UCL Strategic Development Fellowship Award
- May 2013, PhD Studentships
- May 2013, MRC award the four UK Health Informatics Research Centres (HiRC-UK) £20m Infrastructure grant
- 1-2 May 2013, National Launch of the Network, Royal College of Physicians, London
- May 2013: ‘Cloud’ to help UCL researchers with blue-sky thinking
- December 2012: First CHAPTER retreat
- August 2012: New Centre announced
- February 2013: Series on prognosis research published in two medical journals will help improve outcomes for patients
- May 2013: UCLPartners get the green light to improve the health care of over six million people
- May 2013: Calls for an Administrative Data Research Network (ADRN)
- March 2013: Announcement: Expressions of interest for Medical Bioinformatics – building capability, capacity and infrastructure
- June 2013: Research: Failure to use linked health records may lead to biased disease estimates ...
- New PhD studentship opportunities
- New linkage research shows fall in child mortality
- New research shows value of linkage
- Over £7m for government data project
- Farr Director interviewed by Nature magazine
June 2013: Research: Failure to use linked health records may lead to biased disease estimates ...
4 June 2013
In a paper recently published on bmj.com CHAPTER researchers show that
up to 50% of all heart attack cases are missed using just one data source.
These findings may be relevant to other common conditions, such as stroke, and support the wider use of linked multiple record sources by clinicians, policy makers and researchers, they add.
Electronic health records are increasingly used to measure health outcomes, and for research, but records from one part of the health service (e.g. primary care) may not capture health events occurring in other parts of the health system (e.g. hospital care). Researchers compared electronic health records for one major disease event – heart attack (myocardial infarction) – across four national health record sources in England: primary care, hospital care, disease registry and death records.
Previous studies have typically compared only one or two electronic sources.
They identified 21,482 patients with a record of acute myocardial infarction in one or more of the four data sources. Risk factor profiles and one year all cause mortality rates were comparable across records from different sources.
However, they found that each data source missed a substantial proportion of cases. For example, only one third of non-fatal myocardial infarctions were recorded in all three data sources (primary care, hospital care and disease registry), while two thirds were recorded in two sources.
Primary care records were the single most complete source of non-fatal myocardial infarction records (not recording one quarter), hospital records missed one third and the disease registry nearly half.
In other words, acute myocardial infarction was underestimated by 25–50% using one source compared to using all three.
“With the current emphasis on measuring clinical outcomes in health systems and recent plans to use linked data to drive improvements in the care of patients with cardiovascular disease, our study has important implications for practice and policy,” say the authors.
And they say future research should focus on areas such as improving how data are coded, understanding how linkages with primary care, admission to hospital and mortality data compare, and evaluating the quality of the data available in these linked data.
Full article: http://www.bmj.com/content/346/bmj.f2350